Immunity promotes virulence evolution in a malaria model.

Evolutionary models predict that host immunity will shape the evolution of parasite virulence. While some assumptions of these models have been tested, the actual evolutionary outcome of immune selection on virulence has not. Using the mouse malaria model, Plasmodium chabaudi, we experimentally test...

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Bibliographic Details
Main Authors: Margaret J Mackinnon, Andrew F Read
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC434153?pdf=render