The cooperation between hMena overexpression and HER2 signalling in breast cancer.

The cooperation between hMena overexpression and HER2 signalling in breast cancer.

hMena and the epithelial specific isoform hMena(11a) are actin cytoskeleton regulatory proteins belonging to the Ena/VASP family. EGF treatment of breast cancer cell lines upregulates hMena/hMena(11a) expression and phosphorylates hMena(11a), suggesting cross-talk between the ErbB receptor family an...

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Main Authors: Francesca Di Modugno, Marcella Mottolese, Lucia DeMonte, Paola Trono, Michele Balsamo, Andrea Conidi, Elisa Melucci, Irene Terrenato, Francesca Belleudi, Maria Rosaria Torrisi, Massimo Alessio, Angela Santoni, Paola Nisticò
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012725?pdf=render

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http://europepmc.org/articles/PMC3012725?pdf=render

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