NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State
Naive mouse embryonic stem cells (ESCs) can develop multiple fates, but the cellular and molecular processes that enable lineage competence are poorly characterized. Here, we investigated progression from the ESC ground state in defined culture. We utilized downregulation of Rex1::GFPd2 to track the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-07-01
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Series: | Stem Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671117302400 |