The Cytoprotective Effect of Sulfuretin against tert-Butyl Hydroperoxide-Induced Hepatotoxicity through Nrf2/ARE and JNK/ERK MAPK-Mediated Heme Oxygenase-1 Expression

The Cytoprotective Effect of Sulfuretin against tert-Butyl Hydroperoxide-Induced Hepatotoxicity through Nrf2/ARE and JNK/ERK MAPK-Mediated Heme Oxygenase-1 Expression

Sulfuretin is one of the major flavonoid components in Rhus verniciflua Stokes (Anacardiaceae) isolates. In this study, we investigated the protective effects of sulfuretin against tert-butyl hydroperoxide (t-BHP)-induced oxidative injury. The results indicated that the addition of sulfuretin before...

Full description

Bibliographic Details
Main Authors: Dong-Sung Lee, Kyoung-Su Kim, Wonmin Ko, Bin Li, Gil-Saeng Jeong, Jun-Hyeog Jang, Hyuncheol Oh, Youn-Chul Kim
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
sulfuretin
Rhus verniciflua Stokes
HepG2 cells
hepatoprotective
tert-butyl hydroperoxide
oxidative stress
heme oxygenase-1
Online Access:http://www.mdpi.com/1422-0067/15/5/8863

Internet

http://www.mdpi.com/1422-0067/15/5/8863

Similar Items