Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

<p>Abstract</p> <p>Background</p> <p>The Nonsense-Mediated mRNA Decay (NMD) pathway detects and degrades mRNAs containing premature termination codons, thereby preventing the accumulation of potentially detrimental truncated proteins. Intertissue variation in the effici...

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Bibliographic Details
Main Authors: Mazoyer Sylvie, Zhang Chang X, Buisson Monique, Magnin Delphine, Anczuków Olga, Fontanière Sandra, Zetoune Almoutassem B
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/9/83