Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia.

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia.

Acute leukaemias are commonly caused by mutations that corrupt the transcriptional circuitry of haematopoietic stem/progenitor cells. However, the mechanisms underlying large-scale transcriptional reprogramming remain largely unknown. Here we investigated transcriptional reprogramming at genome-scal...

Full description

Bibliographic Details
Main Authors: Nicolas Bonadies, Samuel D Foster, Wai-In Chan, Brynn T Kvinlaug, Dominik Spensberger, Mark A Dawson, Elaine Spooncer, Anthony D Whetton, Andrew J Bannister, Brian J Huntly, Berthold Göttgens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3030562?pdf=render

Internet

http://europepmc.org/articles/PMC3030562?pdf=render

Similar Items