In vitro Assessment of the DNA Damage Response in Dental Mesenchymal Stromal Cells Following Low Dose X-ray Exposure

In vitro Assessment of the DNA Damage Response in Dental Mesenchymal Stromal Cells Following Low Dose X-ray Exposure

Stem cells contained within the dental mesenchymal stromal cell (MSC) population are crucial for tissue homeostasis. Assuring their genomic stability is therefore essential. Exposure of stem cells to ionizing radiation (IR) is potentially detrimental for normal tissue homeostasis. Although it has be...

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Bibliographic Details
Main Authors: Niels Belmans, Liese Gilles, Jonas Welkenhuysen, Randy Vermeesen, Bjorn Baselet, Benjamin Salmon, Sarah Baatout, Reinhilde Jacobs, Stéphane Lucas, Ivo Lambrichts, Marjan Moreels
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Public Health
Subjects:
dental stem cell
DNA damage response
DNA double strand break
low dose radiation exposure
cell cycle
cellular senescence
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2021.584484/full

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https://www.frontiersin.org/articles/10.3389/fpubh.2021.584484/full

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