Immunohistochemistry and Mutation Analysis of <i>SDHx</i> Genes in Carotid Paragangliomas

Immunohistochemistry and Mutation Analysis of <i>SDHx</i> Genes in Carotid Paragangliomas

Carotid paragangliomas (CPGLs) are rare neuroendocrine tumors often associated with mutations in <i>SDHx</i> genes. The immunohistochemistry of succinate dehydrogenase (SDH) subunits has been considered a useful instrument for the prediction of <i>SDHx</i> mutations in paraga...

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Main Authors: Anastasiya V. Snezhkina, Dmitry V. Kalinin, Vladislav S. Pavlov, Elena N. Lukyanova, Alexander L. Golovyuk, Maria S. Fedorova, Elena A. Pudova, Maria V. Savvateeva, Oleg A. Stepanov, Andrey A. Poloznikov, Tatiana B. Demidova, Nataliya V. Melnikova, Alexey A. Dmitriev, George S. Krasnov, Anna V. Kudryavtseva
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
carotid paraganglioma
<i>SDHx</i> genes
mutations
protein expression
exome sequencing
immunohistochemistry
Online Access:https://www.mdpi.com/1422-0067/21/18/6950

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https://www.mdpi.com/1422-0067/21/18/6950

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