Identification of a Circulating Amino Acid Signature in Frail Older Persons with Type 2 Diabetes Mellitus: Results from the Metabofrail Study

Identification of a Circulating Amino Acid Signature in Frail Older Persons with Type 2 Diabetes Mellitus: Results from the Metabofrail Study

Diabetes and frailty are highly prevalent conditions that impact the health status of older adults. Perturbations in protein/amino acid metabolism are associated with both functional impairment and type 2 diabetes mellitus (T2DM). In the present study, we compared the concentrations of a panel of ci...

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Bibliographic Details
Main Authors: Riccardo Calvani, Leocadio Rodriguez-Mañas, Anna Picca, Federico Marini, Alessandra Biancolillo, Olga Laosa, Laura Pedraza, Jacopo Gervasoni, Aniello Primiano, Giorgia Conta, Isabelle Bourdel-Marchasson, Sophie C. Regueme, Roberto Bernabei, Emanuele Marzetti, Alan J. Sinclair, Giovanni Gambassi
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
aging
metabolomics
systems biology
personalized medicine
metabolism
frailty
sarcopenia
muscle wasting
precision medicine
metabolic profiling
Online Access:https://www.mdpi.com/2072-6643/12/1/199

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https://www.mdpi.com/2072-6643/12/1/199

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