Cytotoxicity and Toxicity Evaluation of Xanthone Crude Extract on Hypoxic Human Hepatocellular Carcinoma and Zebrafish (Danio rerio) Embryos

Cytotoxicity and Toxicity Evaluation of Xanthone Crude Extract on Hypoxic Human Hepatocellular Carcinoma and Zebrafish (Danio rerio) Embryos

Xanthone is an organic compound mostly found in mangosteen pericarp and widely known for its anti-proliferating effect on cancer cells. In this study, we evaluated the effects of xanthone crude extract (XCE) and α-mangostin (α-MG) on normoxic and hypoxic human hepatocellular carc...

Full description

Bibliographic Details
Main Authors: Shazrul Fazry, Muhammad Akram Mohd Noordin, Salahuddin Sanusi, Mahanem Mat Noor, Wan Mohd Aizat, Azwan Mat Lazim, Herryawan Ryadi Eziwar Dyari, Nur Hidayah Jamar, Juwairiah Remali, Babul Airianah Othman, Douglas Law, Nik Marzuki Sidik, Yew Hoong Cheah, Yi Chieh Lim
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Toxics
Subjects:
xanthone
α-mangostin
HPLC
MTT proliferation assay
fish embryo toxicity test
Online Access:http://www.mdpi.com/2305-6304/6/4/60

Internet

http://www.mdpi.com/2305-6304/6/4/60

Similar Items