CpG-ODN and MPLA prevent mortality in a murine model of post-hemorrhage-Staphyloccocus aureus pneumonia.

Infections are the most frequent cause of complications in trauma patients. Post-traumatic immune suppression (IS) exposes patients to pneumonia (PN). The main pathogen involved in PN is Methicillin Susceptible Staphylococcus aureus (MSSA). Dendritic cells () may be centrally involved in the IS. We...

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Main Authors: Antoine Roquilly, Laetitia Gautreau, Jean Pierre Segain, Pierre de Coppet, Véronique Sebille, Cédric Jacqueline, Jocelyne Caillon, Gilles Potel, Corinne Lejus, Régis Josien, Karim Asehnoune
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2951351?pdf=render