Underreporting of Dengue-4 in Brazil due to low sensitivity of the NS1 Ag test in routine control programs.

We have identified fifty-eight samples that were positive for Dengue-4 among 119 samples with negative diagnoses for dengue via the Platelia™ dengue NS1 Ag in Aracaju, State of Sergipe, Brazil. We determined that the low sensitivity of the NS1 Ag test could be related to secondary dengue infections...

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Bibliographic Details
Main Authors: Vanessa Ramos Faria Sea, Ana Cecília Ribeiro Cruz, Ricardo Q Gurgel, Bruno Tardelli Diniz Nunes, Eliana Vieira Pinto Silva, Silvio S Dolabella, Roseli La Corte dos Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3662776?pdf=render