Management of Chronic Myeloid Leukemia in Advanced Phase

Management of Chronic Myeloid Leukemia in Advanced Phase

Management of chronic myeloid leukemia (CML) in advanced phases remains a challenge also in the era of tyrosine kinase inhibitors (TKIs) treatment. Cytogenetic clonal evolution and development of resistant mutations represent crucial events that limit the benefit of subsequent therapies in these pat...

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Bibliographic Details
Main Authors: Massimiliano Bonifacio, Fabio Stagno, Luigi Scaffidi, Mauro Krampera, Francesco Di Raimondo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
accelerated phase
blast phase
clonal evolution
molecular monitoring
allogeneic stem cell transplant
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01132/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01132/full

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