BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice

Objective: Bombesin-like receptor 3 (BRS3) is an orphan receptor and Brs3 knockout mice develop obesity with increased food intake and reduced resting metabolic rate and body temperature. The neuronal populations contributing to these effects were examined. Methods: We studied energy metabolism in m...

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Bibliographic Details
Main Authors: Cuiying Xiao, Naili Liu, Haley Province, Ramón A. Piñol, Oksana Gavrilova, Marc L. Reitman
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300429