Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.

BACKGROUND:Stem cell expansion and differentiation is the foundation of emerging cell therapy technologies. The potential applications of human neural progenitor cells (hNPCs) are wide ranging, but a normal cytogenetic profile is important to avoid the risk of tumor formation in clinical trials. FDA...

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Bibliographic Details
Main Authors: Dhruv Sareen, Erin McMillan, Allison D Ebert, Brandon C Shelley, Julie A Johnson, Lorraine F Meisner, Clive N Svendsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2765070?pdf=render