ILB<sup>®</sup> Attenuates Clinical Symptoms and Serum Biomarkers of Oxidative/Nitrosative Stress and Mitochondrial Dysfunction in Patients with Amyotrophic Lateral Sclerosis

ILB<sup>®</sup> Attenuates Clinical Symptoms and Serum Biomarkers of Oxidative/Nitrosative Stress and Mitochondrial Dysfunction in Patients with Amyotrophic Lateral Sclerosis

Oxidative/nitrosative stress and mitochondrial dysfunction is a hallmark of amyotrophic lateral sclerosis (ALS), an invariably fatal progressive neurodegenerative disease. Here, as an exploratory arm of a phase II clinical trial (EudraCT Number 2017-005065-47), we used high performance liquid chroma...

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Bibliographic Details
Main Authors: Giacomo Lazzarino, Renata Mangione, Antonio Belli, Valentina Di Pietro, Zsuzsanna Nagy, Nicholas M. Barnes, Lars Bruce, Bernardo M. Ropero, Lennart I. Persson, Benedetta Manca, Miriam Wissam Saab, Angela M. Amorini, Barbara Tavazzi, Giuseppe Lazzarino, Ann Logan
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
amyotrophic lateral sclerosis
low molecular weight-dextran sulphate
serum biomarkers
energy metabolism
mitochondrial dysfunction
N-acetylaspartate
Online Access:https://www.mdpi.com/2075-4426/11/8/794

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https://www.mdpi.com/2075-4426/11/8/794

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