Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling

The majority of antiviral therapeutics target conserved viral proteins, however, this approach confers selective pressure on the virus and increases the probability of antiviral drug resistance. An alternative therapeutic strategy is to target the host-encoded factors that are required for virus inf...

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Bibliographic Details
Main Authors: Jana L. McCaskill, Sarah Ressel, Andreas Alber, Jane Redford, Ultan F. Power, Jürgen Schwarze, Bernadette M. Dutia, Amy H. Buck
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117301488