Botanicals from the leaves of Acacia sieberiana had better cytotoxic effects than isolated phytochemicals towards MDR cancer cells lines

Botanicals from the leaves of Acacia sieberiana had better cytotoxic effects than isolated phytochemicals towards MDR cancer cells lines

The efficiency of cancer chemotherapy is seriously hampered by the development of resistance of neoplastic cells to cytotoxic agents. In the present investigation, the cytotoxicity of the dichloromethane-methanol (1:1) extract of Acacia sieberiana (ASL), fractions (ASLa-c) from the leaves and isolat...

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Bibliographic Details
Main Authors: Carine M.N. Ngaffo, Rodrigue S.V. Tchangna, Armelle T. Mbaveng, Justin Kamga, Freya M. Harvey, Bonaventure T. Ngadjui, Christian G. Bochet, Victor Kuete
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Heliyon
Subjects:
Acacia sieberiana
Apoptosis
Cytotoxicity
Fabaceae
Multi-drug resistance
Phytochemicals
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020322556

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020322556

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