Serum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease

Serum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease

Acute graft-versus-host disease (aGvHD) is a major cause of adverse outcome in hematopoietic stem cell transplantation (HSCT), with a high incidence (20–50%). A novel, non-invasive diagnostic test to predict for prevalence and severity would enable improved prophylaxis and reduce morbidity. Circulat...

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Bibliographic Details
Main Authors: Rachel E. Crossland, Jean Norden, Mateja Kralj Juric, Kim F. Pearce, Clare Lendrem, Louis A. Bibby, Matthew Collin, Hildegard T. Greinix, Anne M. Dickinson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
graft-versus-host disease
biomarkers
prognosis
microRNA
extracellular vesicles
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01446/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01446/full

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