Metabolism of cholesterol and progesterone is differentially regulated in primary trophoblastic subtypes and might be disturbed in recurrent miscarriages

During pregnancy, extravillous trophoblasts (EVTs) invade the maternal decidua and remodel the local vasculature to establish blood supply for the growing fetus. Compromised EVT function has been linked to aberrant pregnancy associated with maternal and fetal morbidity and mortality. However, metabo...

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Bibliographic Details
Main Authors: Sigrid Vondra, Victoria Kunihs, Tana Eberhart, Karin Eigner, Raimund Bauer, Peter Haslinger, Sandra Haider, Karin Windsperger, Günter Klambauer, Birgit Schütz, Mario Mikula, Xiaowei Zhu, Alexander E. Urban, Roberta L. Hannibal, Julie Baker, Martin Knöfler, Herbert Stangl, Jürgen Pollheimer, Clemens Röhrl
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322902