Domino Multicomponent Approach for the Synthesis of Functionalized Spiro-Indeno[1,2-<i>b</i>]quinoxaline Heterocyclic Hybrids and Their Antimicrobial Activity, Synergistic Effect and Molecular Docking Simulation

Domino Multicomponent Approach for the Synthesis of Functionalized Spiro-Indeno[1,2-<i>b</i>]quinoxaline Heterocyclic Hybrids and Their Antimicrobial Activity, Synergistic Effect and Molecular Docking Simulation

An expedient synthesis of hitherto unexplored novel hybrid heterocycles comprising dispiropyrrolidine, <i>N</i>-styrylpiperidone and indeno[1,2-<i>b</i>]quinoxaline units has been developed via domino multicomponent 1,3-dipolar cycloaddition strategy employing a new class of...

Full description

Bibliographic Details
Main Authors: Abdulrahman I. Almansour, Natarajan Arumugam, Raju Suresh Kumar, Dhaifallah M. Al-thamili, Govindasami Periyasami, Karuppiah Ponmurugan, Naif Abdullah Al-Dhabi, Karthikeyan Perumal, Dhanaraj Premnath
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
domino multicomponent reaction
dispiropyrrolidine
indeno[1,2-<i>b</i>]quinoxaline
docking studies
antimicrobial activity
synergistic effect
Online Access:https://www.mdpi.com/1420-3049/24/10/1962

Internet

https://www.mdpi.com/1420-3049/24/10/1962

Similar Items