Clozapine Pharmacogenetic Studies in Schizophrenia: Efficacy and Agranulocytosis

Clozapine Pharmacogenetic Studies in Schizophrenia: Efficacy and Agranulocytosis

Clozapine is an efficacious atypical antipsychotic for treatment-refractory schizophrenia. Clinical response and appearance of adverse events vary among individual patients receiving clozapine, with genetic and non-genetic factors potentially contributing to individual variabilities. Pharmacogenetic...

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Bibliographic Details
Main Authors: Shusuke Numata, Hidehiro Umehara, Tetsuro Ohmori, Ryota Hashimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
clozapine
schizophrenia
clinical response
agranulocytosis
pharmacogenetics
SNP
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01049/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01049/full

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