Germline mutation at codon 1309 of the adenomatous polyposis coli gene and exteracolonic manifestations in familial adenomatous polyposis

Background: Familial adenomatous polyposis (FAP) is the most common components polyposis syndromes. It incidence is for less than 1 percent of colorectal cancer cases. FAP is characterized by germline mutations in the adenomatous polyposis coli (APC) gene. Generally, there are hundreds to thousands...

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Bibliographic Details
Main Authors: Faegheh Behboudi Farahbakhsh, Hossein Maghsoudi, Hamid Asadzadeh Aghdaei, Ehsan Nazemalhosseini-Mojarad
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2017-07-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5584&slc_lang=en&sid=1