Synthesis and evaluation of novel chromanone and quinolinone analogues of uniflorol as anti-leishmanial agents

Within this work, we describe the design and synthesis of a range of novel chromanones and quinolinones, based on natural products reported to possess anti-leishmanial action. The core heterocycles were obtained either via classical or ionic liquid mediated Kabbe condensation in the case of chromano...

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Bibliographic Details
Main Authors: Helena Castro, Tânia Cruz, Patrícia de Aguiar Amaral, Paula da Silva Cardoso, Ahmed Alsaffar, Patrick Farrell, Ana M. Tomás, James W. Barlow
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402030459X