CD11b⁺, Ly6G⁺ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection.

The goal of the innate immune system is containment of a pathogen at the site of infection prior to the initiation of an effective adaptive immune response. However, effector mechanisms must be kept in check to combat the pathogen while simultaneously limiting undesirable destruction of tissue resul...

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Bibliographic Details
Main Authors: Matthew A Fischer, Michael L Davies, Irene E Reider, Erica L Heipertz, Melanie R Epler, Janet J Sei, Molly A Ingersoll, Nico Van Rooijen, Gwendalyn J Randolph, Christopher C Norbury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3213107?pdf=render