MiR-135-5p-p62 Axis Regulates Autophagic Flux, Tumorigenic Potential, and Cellular Interactions Mediated by Extracellular Vesicles During Allergic Inflammation

MiR-135-5p-p62 Axis Regulates Autophagic Flux, Tumorigenic Potential, and Cellular Interactions Mediated by Extracellular Vesicles During Allergic Inflammation

The objective of this study was to investigate the relationship between autophagy and allergic inflammation. In vitro allergic inflammation was accompanied by an increased autophagic flux in rat basophilic leukemia (RBL2H3) cells. 3-MA, an inhibitor of autophagic processes, negatively regulated alle...

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Bibliographic Details
Main Authors: Misun Kim, Yeongseo Park, Yoojung Kwon, Youngmi Kim, Jaehwan Byun, Myeong Seon Jeong, Han-Ul Kim, Hyun Suk Jung, Ji Young Mun, Dooil Jeoung
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
P62
miR-135
extracellular vesicles
cellular interactions
allergic inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00738/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00738/full

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