Variations in the Blood Phenytoin Levels during Long-Term Combined Treatment with S-1 and Phenytoin

Variations in the Blood Phenytoin Levels during Long-Term Combined Treatment with S-1 and Phenytoin

Although combination therapy with the oral fluoropyrimidine anticancer drug S-1 and the anticonvulsant phenytoin (PHT) is known to increase blood levels of PHT and the risk of intoxication, reports on long-term monitoring of blood levels of PHT during combined S-1 and PHT treatment and a thorough un...

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Bibliographic Details
Main Authors: Yutaka Negoro, Takashi Higashi, Hiroaki Matsuoka, Kyohei Watanabe, Toshiaki Igarashi, Yuichiro Kayano, Ryoichi Yano, Toshiaki Nakamura, Mikio Masada
Format: Article
Language:English
Published: Karger Publishers 2014-09-01
Series:Case Reports in Oncology
Subjects:
S-1
Phenytoin
Drug interaction
Therapeutic drug monitoring
Online Access:http://www.karger.com/Article/FullText/368077

Internet

http://www.karger.com/Article/FullText/368077

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