An intergenic non-coding RNA promoter required for histone modifications in the human β-globin chromatin domain.

Transcriptome analyses show a surprisingly large proportion of the mammalian genome is transcribed; much more than can be accounted for by genes and introns alone. Most of this transcription is non-coding in nature and arises from intergenic regions, often overlapping known protein-coding genes in s...

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Main Authors: Emmanuel Debrand, Lyubomira Chakalova, Joanne Miles, Yan-Feng Dai, Beatriz Goyenechea, Sandra Dye, Cameron S Osborne, Alice Horton, Susanna Harju-Baker, Ryan C Pink, Daniel Caley, David R F Carter, Kenneth R Peterson, Peter Fraser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217532