Cellular senescence in cancer: from mechanisms to detection

Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in response to stress. This response also involves other distinct morphological and intracellular changes including alterations in gene expression and epigenetic modifications, elevated macromolecular damage, metabo...

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Bibliographic Details
Main Authors: Hui‐Ling Ou, Reuben Hoffmann, Cristina González‐López, Gary J. Doherty, James E. Korkola, Daniel Muñoz‐Espín
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12807