Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reaction
A series of functionalized spiro[indoline-3,2'-oxiran]-2-ones was efficiently synthesized by Darzens reaction of phenacyl bromides with isatins both with N-alkyl groups and without N-substituent in the presence of potassium carbonate as a base catalyst. When two equivalents phenacyl bromides we...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2013-05-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.9.105 |