Activation of the Ion Channel TRPV4 Induces Epithelial to Mesenchymal Transition in Breast Cancer Cells

Activation of the Ion Channel TRPV4 Induces Epithelial to Mesenchymal Transition in Breast Cancer Cells

Epithelial to mesenchymal transition (EMT) in cancer is important in therapeutic resistance and invasiveness. Calcium signaling is key to the induction of EMT in breast cancer cells. Although inhibition of specific calcium-permeable ion channels regulates the induction of a sub-set of EMT markers in...

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Bibliographic Details
Main Authors: Iman Azimi, Mélanie Robitaille, Kaela Armitage, Choon Leng So, Michael J.G. Milevskiy, Korinne Northwood, Huai Fang Lim, Erik W. Thompson, Sarah J. Roberts-Thomson, Gregory R. Monteith
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
TRPV4
EMT
calcium channel
breast cancer
Online Access:https://www.mdpi.com/1422-0067/21/24/9417

Internet

https://www.mdpi.com/1422-0067/21/24/9417

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