Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells.

Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells.

Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers. Almost all studies using this modality have focused on transfer of TCR from CD8 cytotoxic T lymphocytes (CTLs). The transfer o...

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Bibliographic Details
Main Authors: Kanako Shimizu, Jun Shinga, Satoru Yamasaki, Masami Kawamura, Jan Dörrie, Niels Schaft, Yusuke Sato, Tomonori Iyoda, Shin-Ichiro Fujii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4488262?pdf=render

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http://europepmc.org/articles/PMC4488262?pdf=render

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