Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells.
Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers. Almost all studies using this modality have focused on transfer of TCR from CD8 cytotoxic T lymphocytes (CTLs). The transfer o...
Main Authors: | Kanako Shimizu, Jun Shinga, Satoru Yamasaki, Masami Kawamura, Jan Dörrie, Niels Schaft, Yusuke Sato, Tomonori Iyoda, Shin-Ichiro Fujii |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4488262?pdf=render |
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