Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells

Abstract Transplantation of cultured oral mucosal epithelial cells (OMECs) is a promising treatment strategy for limbal stem cell deficiency. In order to improve the culture method, we investigated the effects of four culture media and tissue harvesting sites on explant attachment, growth, and pheno...

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Bibliographic Details
Main Authors: Rakibul Islam, Jon Roger Eidet, Reza A. Badian, Marit Lippestad, Edward Messelt, May Griffith, Darlene A. Dartt, Tor Paaske Utheim
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00417-z