scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data

scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data

Abstract Background Single-cell RNA sequencing (scRNA-seq) enables the high-throughput quantification of transcriptional profiles in single cells. In contrast to bulk RNA-seq, additional preprocessing steps such as cell barcode identification or unique molecular identifier (UMI) deconvolution are ne...

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Bibliographic Details
Main Authors: Zhe Wang, Junming Hu, W. Evan Johnson, Joshua D. Campbell
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
Scruff
Single-cell RNA-sequencing
Cell barcode demultiplexing
Unique molecular identifier (UMI)
Visualization of data quality
Online Access:http://link.springer.com/article/10.1186/s12859-019-2797-2

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http://link.springer.com/article/10.1186/s12859-019-2797-2

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