Bioinformatics-based prediction of conformational epitopes for Enterovirus A71 and Coxsackievirus A16

Abstract Enterovirus A71 (EV-A71), Coxsackievirus A16 (CV-A16) and CV-A10 are the major causative agents of hand, foot and mouth disease (HFMD). The conformational epitopes play a vital role in monitoring the antigenic evolution, predicting dominant strains and preparing vaccines. In this study, we...

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Bibliographic Details
Main Authors: Liping Wang, Miao Zhu, Yulu Fang, Hao Rong, Liuying Gao, Qi Liao, Lina Zhang, Changzheng Dong
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84891-6