A new LC-MS assay for the quantitative analysis of vitamin K metabolites in human urine[S]

Vitamin K (VK), in both its phylloquinone and menaquinone forms, has been hypothesized to undergo ω- and β-oxidation on its hydrophobic side chain in order to generate the observed urinary metabolites, K acid I and K acid II, which are excreted primarily as glucuronide conjugates. Synthetic standard...

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Bibliographic Details
Main Authors: Matthew G. McDonald, Catherine K. Yeung, Aaron M. Teitelbaum, Amanda L. Johnson, Shinya Fujii, Hiroyuki Kagechika, Allan E. Rettie
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520326018