Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle

Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle

Abstract Developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome, the most severe end of neonatal diabetes mellitus, is caused by mutation in the ATP-sensitive potassium (KATP) channel. In addition to diabetes, DEND patients present muscle weakness as one of the symptoms, and although t...

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Bibliographic Details
Main Authors: Shoichiro Horita, Tomoyuki Ono, Saul Gonzalez-Resines, Yuko Ono, Megumi Yamachi, Songji Zhao, Carmen Domene, Yuko Maejima, Kenju Shimomura
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86121-5

Internet

https://doi.org/10.1038/s41598-021-86121-5

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