Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo.

Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo.

The anti-tumor antibiotic salinomycin (Sal) was recently identified as a selective inhibitor of breast cancer stem cells; however, the effect of Sal on hepatocellular carcinoma (HCC) is not clear. This study aimed to determine the anti-tumor efficacy and mechanism of Sal on HCC. HCC cell lines (HepG...

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Main Authors: Fan Wang, Lei He, Wei-Qi Dai, Ya-Ping Xu, Dong Wu, Chun-Lei Lin, Shu-Mei Wu, Ping Cheng, Yan Zhang, Miao Shen, Chen-Feng Wang, Jie Lu, Ying-Qun Zhou, Xuan-Fu Xu, Ling Xu, Chuan-Yong Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527475?pdf=render

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http://europepmc.org/articles/PMC3527475?pdf=render

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