The role of tumor microenvironment in resistance to anti-angiogenic therapy [version 1; referees: 2 approved]

Anti-angiogenic therapy has been demonstrated to increase progression-free survival in patients with many different solid cancers. Unfortunately, the benefit in overall survival is modest and the rapid emergence of drug resistance is a significant clinical problem. Over the last decade, several mech...

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Bibliographic Details
Main Authors: Shaolin Ma, Sunila Pradeep, Wei Hu, Dikai Zhang, Robert Coleman, Anil Sood
Format: Article
Language:English
Published: F1000 Research Ltd 2018-03-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-326/v1