Identification of Hub Genes Associated With Development and Microenvironment of Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis and Differential Gene Expression Analysis

Identification of Hub Genes Associated With Development and Microenvironment of Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis and Differential Gene Expression Analysis

A further understanding of the molecular mechanism of hepatocellular carcinoma (HCC) is necessary to predict a patient’s prognosis and develop new targeted gene drugs. This study aims to identify essential genes related to HCC. We used the Weighted Gene Co-expression Network Analysis (WGCNA) and dif...

Full description

Bibliographic Details
Main Authors: Qingquan Bai, Haoling Liu, Hongyu Guo, Han Lin, Xuan Song, Ye Jin, Yao Liu, Hongrui Guo, Shuhang Liang, Ruipeng Song, Jiabei Wang, Zhibo Qu, Huaxin Guo, Hongchi Jiang, Lianxin Liu, Haiyan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
hepatocellular carcinoma
differential gene expression analysis
weighted gene co-expression network analysis
tumor microenvironment
overall survival
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.615308/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.615308/full

Similar Items