A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants

A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants

Chronic obstructive pulmonary disease (COPD) is a complex and heritable disease, associated with multiple genetic variants. Specific familial types of COPD may be explained by rare variants, which have not been widely studied. We aimed to discover rare genetic variants underlying COPD through a geno...

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Bibliographic Details
Main Authors: Ivana Nedeljkovic, Natalie Terzikhan, Judith M. Vonk, Diana A. van der Plaat, Lies Lahousse, Cleo C. van Diemen, Brian D. Hobbs, Dandi Qiao, Michael H. Cho, Guy G. Brusselle, Dirkje S. Postma, H. M. Boezen, Cornelia M. van Duijn, Najaf Amin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Genetics
Subjects:
COPD
genetic linkage analysis
genetic isolate
rare variants
chromosome 11
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00133/full

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http://journal.frontiersin.org/article/10.3389/fgene.2018.00133/full

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