Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients.

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients.

Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevanc...

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Bibliographic Details
Main Authors: Caroline Bergenfelz, Anna-Maria Larsson, Kristoffer von Stedingk, Sofia Gruvberger-Saal, Kristina Aaltonen, Sara Jansson, Helena Jernström, Helena Janols, Marlene Wullt, Anders Bredberg, Lisa Rydén, Karin Leandersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4439153?pdf=render

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http://europepmc.org/articles/PMC4439153?pdf=render

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