The in Vitro Inhibitory Effect of Ectromelia Virus Infection on Innate and Adaptive Immune Properties of GM-CSF-Derived Bone Marrow Cells Is Mouse Strain-Independent

The in Vitro Inhibitory Effect of Ectromelia Virus Infection on Innate and Adaptive Immune Properties of GM-CSF-Derived Bone Marrow Cells Is Mouse Strain-Independent

Ectromelia virus (ECTV) belongs to the Orthopoxvirus genus of the Poxviridae family and is a natural pathogen of mice. Certain strains of mice are highly susceptible to ECTV infection and develop mousepox, a lethal disease similar to smallpox of humans caused by variola virus. Currently, the mousepo...

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Bibliographic Details
Main Authors: Lidia Szulc-Dąbrowska, Justyna Struzik, Joanna Cymerys, Anna Winnicka, Zuzanna Nowak, Felix N. Toka, Małgorzata Gieryńska
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Microbiology
Subjects:
ectromelia virus
conventional dendritic cells
Th polarization
immunosuppression
viral evasion strategies
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02539/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02539/full

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