Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle

Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle

Introduction: Hydrochlorothiazide has a negative influence on penile erection but little is known about the mechanism(s) involved. Aims: To characterize the effects of this diuretic on mouse corpus cavernosum (CC) smooth muscle in vitro and ex vivo. Methods: CC strips of C57BL/6 mice (12–16 weeks ol...

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Bibliographic Details
Main Authors: Thiago Gagliano-Jucá, MD, PhD, Mauro Napolitano, PhD, Fernanda Del Grossi Ferraz Carvalho, PhD, Rafael Campos, MPhil, Fabíola Zakia Mónica, PhD, Mário Angelo Claudino, PhD, Edson Antunes, PhD, Anibal Gil Lopes, MD, PhD, Gilberto De Nucci, MD, PhD
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Sexual Medicine
Subjects:
Corpus Cavernosum
Erectile Dysfunction
Adrenergic Mechanism
Diuretics
Online Access:http://www.sciencedirect.com/science/article/pii/S2050116116000295

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http://www.sciencedirect.com/science/article/pii/S2050116116000295

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