Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.

BACKGROUND: Delayed fracture healing causes substantial disability and usually requires additional surgical treatments. Pharmacologic management to improve fracture repair would substantially improve patient outcome. The signaling pathways regulating bone healing are beginning to be unraveled, and t...

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Bibliographic Details
Main Authors: Yan Chen, Heather C Whetstone, Alvin C Lin, Puviindran Nadesan, Qingxia Wei, Raymond Poon, Benjamin A Alman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1950214?pdf=render