Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome‐Wide Association Study in Multiple Cohorts

Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome‐Wide Association Study in Multiple Cohorts

Abstract Germline polymorphisms are linked with differential survival outcomes in cancers but are not well studied in nasopharyngeal carcinoma (NPC). Here, a two‐phase association study is conducted to discover germline polymorphisms that are associated with the prognosis of NPC. The discovery phase...

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Bibliographic Details
Main Authors: Yun‐Miao Guo, Jie‐Rong Chen, Yan‐Chun Feng, Melvin L. K. Chua, Yanni Zeng, Edwin Pun Hui, Allen K. C. Chan, Lin‐Quan Tang, Lin Wang, Qian Cui, Hui‐Qiong Han, Chun‐Ling Luo, Guo‐Wang Lin, Yan Liang, Yang Liu, Zhong‐Lian He, Yu‐Xiang Liu, Pan‐Pan Wei, Chu‐Jun Liu, Wan Peng, Bo‐Wei Han, Xiao‐Yu Zuo, Enya H. W. Ong, Eugenia L. L. Yeo, Kar Perng Low, Gek San Tan, Tony K. H. Lim, Jacqueline S. G. Hwang, Bo Li, Qi‐Sheng Feng, Xiaojun Xia, Yun‐Fei Xia, Josephine Ko, Wei Dai, Maria L. Lung, Anthony T. C. Chan, Dennis Y. M. Lo, Mu‐Sheng Zeng, Hai‐Qiang Mai, Jianjun Liu, Yi‐Xin Zeng, Jin‐Xin Bei
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Advanced Science
Subjects:
biomarkers
cancer prognosis
germline polymorphisms
nasopharyngeal carcinoma
RPA1
single nucleotide polymorphisms
Online Access:https://doi.org/10.1002/advs.201903727

Internet

https://doi.org/10.1002/advs.201903727

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