The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells
Abstract Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was described that PHB (Prohibitin) 1 an...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-09-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-021-00352-9 |