N-octanoyl dopamine, a non-hemodyanic dopamine derivative, for cell protection during hypothermic organ preservation.

BACKGROUND: Although donor dopamine treatment reduces the requirement for post transplantation dialysis in renal transplant recipients, implementation of dopamine in donor management is hampered by its hemodynamic side-effects. Therefore novel dopamine derivatives lacking any hemodynamic actions and...

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Bibliographic Details
Main Authors: Ralf M Lösel, Ulf Schnetzke, Paul T Brinkkoetter, Hui Song, Grietje Beck, Peter Schnuelle, Simone Höger, Martin Wehling, Benito A Yard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2838791?pdf=render