binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions

Abstract Background In this era of data science-driven bioinformatics, machine learning research has focused on feature selection as users want more interpretation and post-hoc analyses for biomarker detection. However, when there are more features (i.e., transcripts) than samples (i.e., mice or hum...

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Bibliographic Details
Main Authors: Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Wesley Chiu, Liam Wilson, Hao Helen Zhang, Yves A. Lussier
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s12859-020-03718-9